Females... 1. The world will be a better place. 2. I can take a nap in cleavage. 3. Muff diving would be amazing. 4. Fingernails and toenails would be like canvasses for painting. 5. Stay fit getting exercise climbing up the back of lined stockings or fishnets. ... oh, where do the benefits end?
The only real downside is voice. A 50-foot giant would have a very very pitched low voice and may not be heard well but more felt as it would be very loud vibration... like whale sounds. en. wikipedia. org/.../Whale_vocalization
Being male, I choose all males because then I get to be a 50ft giant.
Women are generally smaller than men on average so it would mess up human dynamics if the were bigger. Average sized penises are already said to be too small for the majority of women so imagine how bad the problem would be if women were 50 ft giants with massive vaginas.