I'm a 19 year old virgin, weigh about 280ish...and I've just never had the courage to go and talk to girls, I've had one girlfriend that was like a week long because her life was to hectic, I really need help!
tell a joke, or like non_vague said use a ice breaker just don't over do it. you might come to find that a lot of us women like the shy guys, because it just means that they have a lot to tell and say, it also means that the talks will probably never get boring because the girl is your girls to tell everything to. Also, please do not rush into sex right away just because you are a virgin.
Go to a concert or a show, something that YOU'RE interested in and like. Take a few friends (because noone likes to fly solo) and scope out the place for anyone that you find attractive. Stand near them (if its a concert) and strike up a casual convo about a song you love or something. Going to a concert is kind of thinking ahead of the game because if you both have the same taste in music (which is a given since you're both there), then you're bound to have more stuff in common as well. Also, you never know, someone might approach you as well :) Good luck!