I've had quite a few piercings but oddly enough the centre of my ear (where the cartilage is thickest) hurt the most. Hurt during as well as for ages afterward. Shoot, it hurt more than my tats, actually.
I don't have any piercings, but my friend got her ladyparts pierced, and she's going back to get them pierced like 3 more times, she says 'cos the piercer was cute, hahaha. And when he said 'You ready?', while kneeling down there, she got to say 'Yeah, yeah, poke away'