Oh, come on. This crap has a long history. I frequently feel annoyed by some particular questions and takes. Of course, there are some users who constantly write some questions and takes which have been promoted for so many times. (Honestly, I even don't understand why their s**t are always promoted and/or recommended).
Anyway, I want to mute something on my timeline. They are so annoyed yet they are promoted for so many times.
I like your idea. I think users have been wanting something like that for a while if I'm reading your question right. The best you can do right now is to block the users that bother you and make sure you don't see any of their content by checking your settings.
If you've commented on a question that is sending you bothersome notifications, you can always mute them by going to the question and clicking the three dots at the top right-hand side and choosing "Mute."