Weight Loss Isn't as Simple as You Think

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It's easy to scoff at how simple it "should" be for extremely overweight people to lose weight. "Just eat less and move more," people say.

That seems like an easy enough prescription... right?

It seems insane NOT to do this -- since slimming down is definitely the ticket to better health, a better love life, a better personal life overall, and even greater professional success.

...So why don't overweight people just "eat less and move more"?

Weight Loss Isn't as Simple as You Think

The answer is, honestly, something that neither side really wants to hear.

• The "eat less and move more" people don't want to hear it, because they might have to acknowledge that, at some point, the situation really does get to a point where it's beyond these people's control. And that might knock them off their collective high horse and force them to have (heaven forbid) a little empathy.

• And of course it's painful for overweight people themselves to hear it -- because it's disheartening and demotivating.

But... Reality that sucks is still reality.

Once someone is overweight by a certain amount, the hormones that regulate her/his hunger and satiety are, in polite terms, fucked.
Permanently fucked.

The most recalcitrant views on this stuff tend to be held by the older generation -- which is hardly a surprise, since they came of age in an era when we knew literally nothing about the science of hunger and satiety.

We still don't know much -- but, until just over 20 years ago, we knew quite literally nothing at all.

Weight Loss Isn't as Simple as You Think

The head honcho in charge of all this stuff appears to be a hormone called leptin, which wasn't even discovered until 1994.

The current state of knowledge on leptin -- well, "current" as of about 2 years ago, meaning already somewhat out-of-date but good enough for starters -- is here.

Long story made short: Leptin is the "satiety hormone". One of its most important functions is to tell people it's time to stop eating. Yes, that's an oversimplification -- as is absolutely everything in human biology -- but it's a decent first-order approximation, and it's more than good enough as a basis for understanding what's happening here.

Now, see, this leptin stuff is produced by fat cells.
That SHOULD be a defense against getting too fat. It's supposed to work like this:

• Accumulate enough fat cells...

• ...thus, produce more leptin...

• ...and that should make you reduce your food intake, by killing your appetite.

But, for some reason, in a lot of today's obese people, that isn't happening.

Once people reach a certain level of overweight, their bodies just stop "listening" to leptin... and they stay hungry... and they keep overeating.

There's a certain level of overweight that shuts down the body's ability to regulate its own appetite.


No one really knows what causes this phenomenon ("leptin resistance" or "leptin insensitivity"). Some examples of pioneering research are here and here.

If you slog through that second link, you'll notice this: "Certainly however, combinatorial approaches appear to hold some promise for clinical leptin therapy"... ahahahaha. Do you know what that actually means?
"Combinatorial approaches", in medicine, literally means throwing completely random combinations of drugs and/or therapies at some problem or condition, and simply observing whether (and/or how well) each combination works.

The best response so far, from the best and brightest in all of medical science, is ... "throw a bunch of random stuff at the wall, and see what sticks".
That's how stubborn this problem is.

That's literally the best weapon in our arsenal right now, against this obesity monster... Random guessing.

Like pressing random buttons on a video-game controller to try to beat the big boss.

Weight Loss Isn't as Simple as You Think

Encouraging, huh?

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So... What's the actual experience of people who reach this level of overweight? Why DO they have such a hard time "eating less and moving more"?

Well...

I'm all for personal responsibility, and seizing the day, and all that... but, in this case, things can quickly reach a point where causation starts going in both directions.

After a certain point, obesity can actually CAUSE overeating and lack of exercise!

It's fucking crazy, but, this is actually true. This is really a real thing that is real.

What happens when people reach this point?

Weight Loss Isn't as Simple as You Think

• As already discussed, their response to leptin is "broken", so they literally NEVER feel full.

People who have passed this "point of no return" are ALWAYS hungry. Even if they overeat to the point of vomiting, they still FEEL hungry.

They literally become physically lazier. Because of changes in their bodies' responses to insulin, they start to move LESS. Both in terms of actually moving around from point A to point B, and in terms of general restless fidgeting (which can burn up to several hundred calories a day, in particularly restless/"fidgety" people).

Just moving around like a normal person becomes an epic struggle -- let alone trying to "move more".

• Worst of all... These things don't get any better when they DO lose weight.

This is where the stakes get high, folks.

According to pretty much the entire corpus of current research -- see here, here, and here -- once someone's response to leptin is fucked, it stays that way in perpetuity. For the rest of this earthly life.

From that last study... "The relation between leptin and hunger was not influenced by amount of weight or body fat loss." That's about as blunt as the text of a medical study is gonna get, kiddies.

Someone who gets up to 250 or 300 pounds is going to be stuck with the appetite of a 250- or 300-pound person... or even an unlimited appetite.
FOREVER.
And ever and ever and ever.

...Yep. Say goodbye to EVER feeling satisfied by food again.

Weight Loss Isn't as Simple as You Think

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So... Can ANYTHING be done about this?

Yes... BUT.

But but but but.

It ain't gonna be easy.

And when I say "it ain't gonna be easy", I mean it's damn well going to be the hardest, most miserable, most unforgiving, most initially unrewarding thing EVER. It's going to be a test of every last molecule of stubbornness and dedication and grit at the bottom of someone's heart and soul.

In short, it's gonna fuckin' suck.

The only way to break the cycle is ... NO starches, NO sugars, NO dairy, and, generally, NO carbohydrates AT ALL, other than tiny amounts of fibrous vegetables.
For MONTHS.

Or even YEARS.

That's NO as in NO.

As in ZERO.

Weight Loss Isn't as Simple as You Think

That's NO to samples at Costco or Trader Joe's, NO to snack foods, NO to your mother's and grandmother's cooking, NO to the finger food at parties, and NO to basically every single other form of social eating known to mankind.

For months.

Or years.

This is one of those "If you're not ALL in, then you're out" things. Even smallish amounts of carbohydrate will maintain leptin resistance, and maintain all of the awful things described above -- as amply documented in studies such as this one, this other one, and this one right here, too.

The fastest results -- where "fastest" can absolutely still mean a period of months or years, depending on the level of overweight we're talking about -- will come from what's known as a PSMF diet. This means eating as close as humanly possible to ALL protein, ZERO fat, and ZERO carbohydrate. (Rare moments of weakness should involve fat, and NEVER carbohydrate.)

PSMF is EPICALLY shitty, and INCREDIBLY difficult to stick to. It's so grueling that even professional fitness models -- whose living literally depends on this stuff -- can hardly stick to it for more than a month or so.

Weight Loss Isn't as Simple as You Think

But... for those who can stick to it, the weight drops right off (and muscle mass stays on!). And this type of diet is the ONLY thing that has EVER made any headway on resetting that perpetual hunger thing... even a little bit (see the last link above -- the one that says "this one right here, too").

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But...

Obviously, the BEST outcome is ... not to be in that kind of situation in the first place.

The best thing to do, then, is to nip this problem in the bud -- before it becomes a problem in the first place.

Be BRUTALLY honest with yourself about your diet and exercise habits.

If you correct small problems, you'll never have to face BIG problems.

Ask a friend, or two, or six, to help keep you on track, too -- especially if you tend to eat according to your emotions or your monthly cycle, when you have the least control over yourself in general.

Make sure these are REAL friends, and not "frenemies" who would secretly enjoy seeing you gain weight. Those are the kinds of "friends" that are best left in the past tense.

Weight Loss Isn't as Simple as You Think

But, when you have real friends on your side, it's easier to stay on top of your game. As they say, when you replace "I" with "we"... you turn illness into wellness.

Stay healthy, kids.

#BATTLEROYALE #TeamRJ

Weight Loss Isn't as Simple as You Think
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