Do you acknowledge their existence? Should they pull themselves up by the bootstraps? Are they just weakness being weeded out by evolution? Do you feel for them? Identify with them? Do they disgust you? Have you ever felt like a loser? Can there be winners without losers? Is there such a thing as luck in life?
Until we acknowledge the fact that life is inherently unfair, we're not going to acknowlegde the people who lose out.
And the resulting society will become increasingly gruesome and inhuman.