Most Helpful Girl
Depends on who it is.
If it's someone I consider an acquaintance, I personally, might give it a second thought, to realized that who ever asked me probably had feelings for me. After that I shrug it off. What they say won't affect me, and I make sure I don't talk to them.
If it's a friend, I'll certainly play it over in my head and ask myself if rejecting them was the right choice. Sometimes I reconsider straightening things out, or if I need to maybe accept it. Certainly I feel guilty because I hold each of my friends dear, male or female.