When to move on?

When should I cut my losses. For example if there is a girl that I am interested in used to return my calls and answer, but only does it now rarely? I don't know if I should be persistent and try to pursue her, or just cut my losses and call it a day?
Updates:
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The thing is I don't know if now is the point of no return.
+1 y
How to stop thinking about the girl, because I like someone said she probably has not even thought about me once. I want to become more detached and able to not show much emotion?
When to move on?
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