Most Helpful Girl
If a relationship is toxic or unhealthy then it would be a good idea to break up. If one and/or both of you is unhappy in the relationship then it would be a good idea to break up. If one person just can't handle the pressure of a relationship on top of college, projects etc.
Most Helpful Guy
If you are getting verbally abused and nagged and you have sacrificed who you are, then you should break up.