Most Helpful Girl
No. Someday, you may need them, they may need you.. or if you have children in the future, they may need their grandparents. Unless your family is 100% beyond saving psychotic and you have real cause to think that they may literally attempt to murder you or sabotage your life completely, it's best to not burn those bridges.
Most Helpful Guy
Any particular reason that you don't want to have any contact? Maybe they refused to bail you out after you were arrested?