When you broke up with someone, have you ever lost someone else?

When you broke up with someone, have you ever lost someone else?
When I broke up with my ex, my sister took her side and as of now has decided I'm good as dead to her.
What about you? Has this ever happened to you?
Updates:
23 d
Late, but she texted me this morning and maybe we'll arrange to meet somewhere and talk things over.
When you broke up with someone, have you ever lost someone else?
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