Are shy guys most of the time doomed with girls?
Most Helpful Girl
Because a lot of them are socially awkward and/or have Asperger's, because they are scared of looking at girls much less speak to them and God forbid asking them out.
Girls can't ever know if they like them because they are frightened of showing any interest.
By these terms - it seems unlikely any girl will ask a shy guy out unless she's determined to get to know him and make a conscious effort.
Most girls (as humans in general) like to feel desired and admired.
With a shy guy this doesn't happen.