I feel so guilty?

My sister of 31... is depressed.. i haven't spoken to her in 3 years... last time i went to her door in oktober and i said i can help if she wants too... she got angry and said no 3 times... i really miss my sister man... people kinda. broke us up and i feel bad about it... i have been pushing other friends away cause i miss her too much i feel like why am i spending time with them when i can have my sister?
I feel so guilty?
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