What should I have to know?

I just realized Im 21 and never had the sex talk, the public middle school didn't do anything , the high school health teacher was also the gym teacher so we learned more of disease and health stuff. For the other high school when I moved only taken summer school health and simple more and easy A

My parents were never talked of anything of life and school, from being busy and not well of parenting honestly. I with my grandma now and don't talk about personal stuff with her really and do stuff on my own.
What should I have to know?
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