There are multiple reasons why a guy might not want to have anything to do with promiscuous women. It usually based on jealousy, hatred, misogyny or biases.
Promiscuous women don't want to have sex with them
If promiscuous women wanted to have sex with them, then they shouldn't be complaining. Right? Part of the reason has to be because those 'sluts' are not lining up to suck their dicks which frustrates them a lot. Sexually undesirable men know that their only way to most easily get available sex is through a relationship. They assume that if promiscuity is promoted in women, then women will forego relationships with men and choose to sleep with men that are sexually desirable.
They are jealous that promiscuous women can easily get laid
This jealousy just adds more to the hatred. It's true that it's easier for the average woman to get laid versus the average man. It makes them jealous that it's not that easy for them to get laid, and that jealousy makes them not want to have anything to do with promiscuous women.
Their homophobia makes them disgusted by women who slept with multiple men
They may subconsciously have this weird idea that if multiple dicks went into the same vagina, then it's 'gay' to have sex with her. These type of men also have developed this weird idea that women who sleep around are not 'real women,' and that they are no different from gay men.
They assume she is misandrist
You know how if a man objectifies women as 'pieces of meat,' then women would call him a misogynist. Well it's pretty much the same thing here because men may assume that promiscuous women objectify men as 'pieces of meat.' To add more to the picture, most men view promiscuous women (and anyone who supports promiscuity in women) as 'feminists.' They generally associate feminists with misandrists, so it's not surprising if they subconsciously view a promiscuous woman as a misandrist.
They fear being objectified in the same way they objectify women
Sex is physical and physical characteristics influence who we want and don't want to have a one night stand with. A lot of men like to pretend that objectification is not a bad thing. No one likes to be objectified, especially men. I noticed that most men much prefer to be perceived and treated as people instead of objects. Cause god forbid if women are the same way, right? If more women started to vocally objectify men in the same way men objectify women, then men will start to become more insecure about their looks which are things they barely have control over.
They think she might have an std
This is the most rational reason so far. The more promiscuous you are, the odds of you having an std is higher.
They think she is more likely to cheat
Paternal uncertainty is a real thing. Men are never 100% sure of who their kids are, and this instinct has always existed since the dawn of time. If his woman is likely to cheat on him, then that would make him more uncertain about his blood relation to his children.
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