There's no real way to tell...at least I don't think there is. If anything I would be thinking she's staring at me thinking "why is that guy staring at me?". Sometimes it's obvious they are looking because they like what they see..but to tell if she has the hots for you..that's kind of a different story. I don't think I've ever gone up to a girl and talked to her based on what you're asking. Too much of a risk of me embarrassing myself.
I would say if a girl does it more than once, then yes. Otherwise, you can't be too sure, she might have just randomly seen you from across the room, although if she locks eyes with you for a few seconds, then she may be interested.
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Home > Fashion & Beauty > If a girl locked eyes with you for a moment in time just once, would you know that she liked you?