And feel free to also say what language it's in and what it means!
My favorite is "raison d'têre. Which is French for "reason for existence".
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I like Sic transit gloria mundi, from Latin: There goes the glory of the world.
Usually, it's used ironically, when everything goes wrong... or when someone is conceited and you want to make fun of them. There are a lot of occasions where this phrase can be used, seriously or.. in jest!!!1