Most Helpful Guy
I can't decide between Cait, Piper and Curie for romance options in terms of a favorite.
I can't decide between Hancock, Nick or Strong for companions.
Most Helpful Girl
Dogmeat... he is sickly vicious!.. and finds loot you can't see... he is a good dog.
And Eva from the robots addon pack... i modded her to have Mr. Handy's thruster, heavy armor, and two laser sniper rifles... and she is always reminding me to collect EVERYTHING so i can upgrade her.