I always thought "pretty" is the most significant one.. in English words when you describe someone :) but what do you think?
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Gorgeous, Lovely, Beautiful, Pretty are typically reserved for women.
Handsome is typically reserved for men.
Adorable, Hot, Cute, Fine, and Charming can be used for either gender.
Each has different shades of meaning. I think Gorgeous points at a glamorous side of beauty. Lovely and Pretty are about the same, but Pretty may be slightly more complimentary and Lovely more romantic.
Hot and Fine are terms that are not exactly 'crass', not at all, but definitely more 'unrefined.' It is the words of the proletariat. I don't see elite people talking like that.
Charming accentuates the person's personality more than their physical beauty. Adorable is a mixed term (and sometimes its relative Cute, but seldomly so) -- it can be used in a very non-sexual, non-romantic, non-interested way BUT it can also be used to mean exactly those things (more likely if a woman says it) but less so if a man says it.
I think vernacular is a big issue too. I am using the vernacular of my social class and geographical location. You should get different results in other places...