What are the major issues that have kept you from being as successful/happy in your life as you otherwise could be?

I mean in terms of success in relationships, career, finance, self-fulfillment - wherever you feel you have come up short.

For me, the big bugaboos have been procrastination and my OCD. When I was younger social discomfort was also a factor but that is largely in the past now.

What are the major issues that have kept you from being as successful/happy in your life as you otherwise could be?
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