Why don't guys ever like me back?

Ever since high school no guy has ever liked me back. So far I've been rejected by like 7 or 8 guys. I'm 18 years old and still don't have a boyfriend and never been kissed. I started liking this new guy. In person he'd always stare at me and give me signs of a guy who likes me. Now that I'm not going to be able to see him in person anymore I decided to message him on aim and facebook. He either takes forever to reply, ends the conversation fast, or just never replies. I'm really hurt but it's like I saw it coming. In high school guys always thought I was weird and they made fun of me. Guys would always make fun of my voice. My sister is always getting all the guys. She has so many guys chasing after her. She's already been kissed and has had a boyfriend. So far I just see no point in liking any guy because I feel like I'm going to be rejected. I just want to give up. The only guys that go after me are the guys who try to get with every girl just for sex. Honestly, it hurts a lot because I have really low self esteem as it is.
Why don't guys ever like me back?
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