Video and computer games usually don't do well as film adaptations, and there are many reasons why this could be (see one of my previous questions).
However, if it were done correctly - meaning it had the right cast, director, producer and screenwriter, was loyal to the source material, and no political pandering was involved - what video or computer game would you want to see adapted into a film? Or a miniseries?
Whom would you want to play the characters?
If done correctly, I'd be interested to see a StarCraft adaptation.
There are so many different characters and storylines, so I won't list them all here.
There have also been, to my knowledge, two attempts at Doom. Neither of them have been very good. But with the right team, I'd be willing to give it another spin. Maybe with John Cena as the Doom Guy.
