Girls, does your weight affect your boob size?

My girlfriend has two nieces. One is a bit overweight, but not too much, the other is extremely thin. I never really check them out, but I noticed that the skinny one has a lot smaller boobs, and I'm pretty sure they were bigger when she was heavier. So, are boob sizes mostly static or can changes in weight alter them to where they got smaller as she lost weight.

Girls, does your weight affect your boob size?
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