Do you think it's possible to get a vaccine for Fentanyl poisonings? Tens of thousands of people are dying from it, think a vaccine would work?

[sage2021]

Wouldn't that be cool if this whole death by Fentanyl would be knocked out by getting a vaccine 💉 that wouldn't let Fentanyl kill you? The drug cartels would hate that!

[zeitgeist057]

There is a drug to counteract the effects of fentanyl, which is an opioid. It is also good for heroin, morphine, and other opioid overdoses. It is called naloxone, aka "NarCan", and is being widely distributed by health care professionals to help reduce fatal overdoses. You can probably get some free from your health department, and give it to anyone you know at risk.

Naloxone Distribution Program

https://www.dhcs.ca.gov/individuals/Pages/Naloxone_Distribution_Project.aspx

https://www.goodrx.com/naloxone/narcan-naloxone-at-home-free

I have two doses of Narcan that I carry on my motorcycle gear (which I wear a lot), in case I come across a situation where it could save a life.

[sage2021]

@zeitgeist057

The way the Medical examiner that examined by boyfriend when he died from fentanyl mixed with meth saud that the second the FENTYNL enters the body, you're dead that second. Told me how he finds people still holding the lighter they just used seconds before they died.
My boyfriend was found in a very strange position. He said it looked like was kneeling but had his head tucked in near his stomach. He was not flat on the ground though.

Anyway, yes, people could carry around NarCan like they carry around pepper spray if someone tries to attack them. Why not? If what the Medical examiner told me is true, he wouldn't have time to save himself by injection. He'd already be dead.

Maybe you can pursue my idea though. I'd like that.

Thank you for your time and efforts.
Sage2021🌹

[zeitgeist057]

you are right, a person who overdoses is not in a position to administer Narcan. It is something that someone else has to do for you. But I do not agree he was "dead that second", that's not really a thing that happens with drug overdose, it's more like if someone was decapitated or shot in the head. A fentanyl overdose typically will kill someone by stopping their respirations. Then the brain dies over then net 5 minutes or so (though the person is not in pain, because the drug causes euphoria) due to lack of oxygen. Narcan literally cancels the effects of fentanyl and the person will start breathing again. I have watched it happen while working on an ambulance. I was using a device to breathe for the person who had overdosed, we had arrived about 10-15 minutes after the dispatch, and after we administered Narcan (via injection, not nasally), the person started spontaneous respirations again.

Any "vaccine" that prevented someone from dying would also prevent them from getting high off of opiates or feeling any effects from them. The caveat or issue with that is that most drug users will not willingly take something that keeps them from getting high.

[NathanDavis]

interesting... not sure how accurate this is though

"

Fentanyl Vaccine Potential ‘Game Changer’ for Opioid Epidemic

Study Suggests New Vaccine Could Prevent Deadly Opioid from Entering the Brain
By Laurie Fickman 713-743-8454

November 14, 2022

" A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug’s “high.” The breakthrough discovery could have major implications for the nation’s opioid epidemic by becoming a relapse prevention agent for people trying to quit using opioids. While research reveals Opioid Use Disorder (OUD) is treatable, an estimated 80% of those dependent on the drug suffer a relapse.

The findings, published in the journal Pharmaceutics, could not be timelier or more in demand: Over 150 people die every day from overdoses of synthetic opioids including fentanyl, which is 50 times stronger than heroin and 100 times stronger than morphine. Consumption of about 2 milligrams of fentanyl (1/10th the weight of one grain of rice) is likely to be fatal depending on a person’s size.

“We believe these findings could have a significant impact on a very serious problem plaguing society for years – opioid misuse. Our vaccine is able to generate anti-fentanyl antibodies that bind to the consumed fentanyl and prevent it from entering the brain, allowing it to be eliminated out of the body via the kidneys. Thus, the individual will not feel the euphoric effects and can ‘get back on the wagon’ to sobriety,” said the study’s lead author Colin Haile, a research associate professor of psychology at UH and the Texas Institute for Measurement, Evaluation and Statistics (TIMES), and a founding member of the UH Drug Discovery Institute. "

[sage2021]

@NathanDavis
I tried calling that phone number you gave me, but it's been disconnected. 😟

[NathanDavis]

no, I didn't give you a number lol...

I just quoted an actual study

and there's a few studies around about the same topic from different institutions

[provokeesmokee]

Not a vaccine (that's preventative), but there are overdose kits that can help in case of overdoses.

In a bunch of places, it's possible to get overdose kits and training, and for individuals to just have those and use if they find someone in need.

I have several friends who know how to use them and make a point of keeping kits in their cars or at work so they can address overdoses they encounter.

[Fireguy17]

No, I don't think there would be any vaccine that could do that. Opioids take away the bodies drive to breath, so you can keep someone alive like we used to do before narcan by just doing respirations for them.
However, with narcan you just want to titrate it just so they resume breathing on thier own.
Narcan does not last very long so you have to monitor the patient and give more when necessary or add a narcan drip to their IV.
Unlike tv you don't want to dose them the full amount in 1 application, now you have someone who is pissed off because you took their high away.

administering it nasally is not the best choice, you really do not know how much the patient actually received.
Thier nose may be stuffed up and not much may get into their system, half in each nostril is better, and too much they can start having a seizure.
While narcan isn't a cure all it is still better than doing nothing.

[sage2021]

@Fureguy17
So, if you're all alone when the Fentanyl is poisoning you, you have to just lie there and die.
That's what happened to my boyfriend.
May I ask you something I cannot find on the internet? How long is the victim alive once they smoke the fatal dose of Fentanyl and meth? Do they know they are alive for a few minutes before they died because they can't breathe or do they die instantly?
I read 3 more minutes of breathing
5 more minutes of brain activity. So do they know this is happening to them or are they basically dead?
Thank you.

[zeitgeist057]

@sage2021 they likely are not aware because they are in the euphoric state of being high. If you have ever had general anesthesia, that is what it would be like. You could die and not know it, it would be like going to sleep and not waking up. They are alive but not aware.

[sage2021]

@Fireguy17
Thank you for that information. I kept picturing him gasping for air and holding his throat and gasping some more.
I have been under general anesthesia before. You're right. You are not aware the whole time until the nurse with the loud voice keeps calling your name and telling you it's time to wake up now...
When I was younger I would wake up crying.

[Fireguy17]

I will try not to be too graphic, it is not pleasant for anyone involved, the families, friens, even us.
They basically fall asleep, their breathing slows to the point of snoring respiration, then atonal breathing and then they just stop breathing, death follows shorty after, unless there are intentions, narcan, rescue breathing, some cases CPR.
Sometimes despite all of our equipment, education, training, the pd on scene before us it just isn't enough.
Other times the patient comes around and really has no clue what happened.
We had 1 guy who we brought back but he denied taking anything.
We told him we can't treat him unless we know what he took.
Even his friends were telling him to tell us.
I told him we were pumping his chest and breathing for him, still denied taking anything.
Based on most of the patients reactions when they are revived I don't think they know what happened.
Sadly the bodies drive for the next high over shadows everything else, all they want is the next high.
As far as the total time involved before they pass I do not know exactly.
It can depend on the dose, what is in it, their bodies tolerance to what they are taking.
I'm sorry you had to go through this, no one deserves to have to go through any part of it.

[FunkyMonkee]

Well, that WOULD be nice but, they STILL haven't made one for heroine or any of the other deadly drugs that have been around a LOT longer than fentanyl!
The downside of it would be that those that took it would continue to take the drugs because they know they can't get hurt by them.

[Fireguy17]

Heroine is an opioid based drug and narcan can work on those that have OD on that.
Fentanyl is just the latest drug that is being mixed with other drugs to make it stronger.
The sad part is that drug dealers want a few to pass away.
The word gets out that someone passed away from taking their drugs their sales go up.
Narcan does not always work.
Some still pass away even though they have had several doses of it.

[Likes2drive]

They already have something called Narcan if you get to the person in time that does the job, all EMS people have that but there’s no vaccine that could keep people from getting sick from it and dying, I don’t think that’s even possible since it’s not a virus, unless you had a super high metabolism that would burn it off quickly like Captain America, since he can’t even get drunk

[BCA6010]

There's Narcan, but that's not actually a vaccine, nor would a vaccine actually do anything for you in the case of fentanyl. Narcan is typically a nasal spray.

A fatal dose of fentanyl is extremely difficult to prevent the user from dying, mostly because of time. The situation would have to be positively identified, Narcan administered, some more steps similar to CPR, and possibly additional doses of Narcan all in the span of a few minutes, and it may still not be enough.

[worldscolide]

No, and here is the worst part. Say hypothetically you crush the pills, suddenly you have a dust, that if inhaled, can kill you. That shit is stupid dangerous. But bidens worthless piece of shit ass is letting it flood across the border.

[Astarlessnightsky]

No. Fentanyl is a pain killer not a virus/bacteria.

[Billlewis]

No; there are no immunological preventative measures that can be taken to protect against a powerful sedative.

[Anonymous]

Vaccine's are for viruses.