Lending money to acquaintance?

Would you borrow money to a person you know, but not a close friend? You know that this person is not very responsible and you do not contact him(her) very often. But he(she) is in trouble and asks you for help. Say, 1000$. For 2 weeks.
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UPD: Well, guys, as I can see no one is ready to help, to trust a random person. It's understandable.

What if you like this person and if you refuse - you will have chance to check this person and know him(her) better?
Lending money to acquaintance?
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