Are guys usually afraid of making any female friend angry?

One guy thought he made me angry today, and he was so concerned about it. I told him it's not him and explained what I was upset about. However, later, I couldn't understand why he was so concerned so I asked and he said it's because he thought it was his fault. Do guys usually react this way? (FYI, I'm not even really his friend)

Are guys usually afraid of making any female friend angry?
Post Opinion