How do you know if your anti-anxiety/despression meds are working?

Right now I have been taking .5 mg of Klonopin and 25 mg of Sertraline (Zoloft) for 2 weeks now. I am noticing how my appetite is decreased and my desire to masturbate is nonexistent. Aside from that, I'm not really seeing any effects of the meds...

if the meds are working, am I supposed to immediately feel like I'm floating on cloud 9 or feel happy right away? or do meds take some weeks to build up in your system in order for the mental and physical effects to be noticeable?
How do you know if your anti-anxiety/despression meds are working?
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