I HATE my sister in law with a PASSION, and I know she doesn't like me or my family either. What to do?

I am fed up with my sister in law. She's the most manipulative person I have ever met, she is constantly manipulating my brother and because of her fault my brother is not as close to our family like he was before he met her. She keep manipulating him to like her family more. I keep my distance, but every second I find out she is throwing low blows from a distance. She always has my families name in her mouth. I am sick of her shit.
I HATE my sister in law with a PASSION, and I know she doesn't like me or my family either. What to do?
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