At what point do you move when you don't like the local laws?

There are jobs in every state and you have legs, nobody is tied to live where they are.
Thou it may be true your bonds to a particular piece of land or community are defined by the conditions of your state. Said conditions as much include your state's historic laws as it's geography and natural resources.
So why do you leave? Is it a new policy or environment or have you yourself changed as to no longer be compatible with the conditions that brought your family and yourself to live among them?
At what point do you vote with your feet?
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