Guys who get frustrated with girls being so insecure about their looks, are there any times when girls have good reason to be insecure?

I mean, what about girls who constantly are in situations whereby they are treated differently than a more attractive girl nearby. At a certain point, doesn't it become clear that it's not just in her head that she's unattractive, and that her being 'hard on herself' is actually quite justified?

Guys who get frustrated with girls being so insecure about their looks, are there any times when girls have good reason to be insecure?
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