How realistic do you think it is that no one has wanted to be a specific person's friend in all three stages of their life (kid, teenager, adulthood)?

It seems crazy to me that people could go all three stages of their life without having a single friend. I don't know anyone like that, but have heard stories

Not realistic at all
It's rare but realistic
Something would have to be wrong with that individual for it to be realistic
Very realistic
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How realistic do you think it is that no one has wanted to be a specific person's friend in all three stages of their life (kid, teenager, adulthood)?
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