What do I do for my niece?

I really think my niece is turning into a lesbian. And I feel so horrible because I don’t want her to live that life. That life isn’t a good life. She’ll become depressed and miserable like all lesbians. No matter how “happy” they claim to be…. Anyways, I think my older brother failed her as a parent. He always had her helping him with stuff around the house, and I think it made her confused into thinking she can be a boy. She wears boy clothes now. And I think it’s dumb how my brother isn’t doing anything about that. I think it also doesn’t help that his wife and him don’t have a good relationship. So she doesn’t see what a man and woman relationship can be. At this point, I don’t know if whether to tell her that living as a lesbian isn’t the best choice? Or to just stay out of her life?

What do I do for my niece?
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