I'm 35, she's 22, will this work?

We just got involved, both of us are really into each other and both of us have no problem with the age difference. She is mature for her age, and I look A LOT younger than my 35 years (thanks to my Asian blood). Last year I was involved with a 49 year old woman, so I know all about a generation gap. But, our friends are telling us that it will never work, it sucks not to have their support. My parents are 11 years age difference, and her's are 12 years apart. I don't see what the problem is, age is just a number as long as respect is given. Any others involved with somebody with a big age gap have any suggestions? Thanks!
I'm 35, she's 22, will this work?
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