Depends on what kind of guy it is, and what kind of kiss it is. If it's like a double tap and hug kiss, Latin style, then he might not care.
This actually happened to me once. A girl who's interested in me works at a local hangout. She'd been flirting with me the whole evening, but I didn't respond too much, I was just looking to spend some time with my friends. At the end she planted a kiss on my cheek from behind, while I was sitting and chatting with a mate of mine. It really turned me off, though. I'm sort of flattered, but a kiss for no reason is kind of creepy.
Hoooowever, I'm really, really not the touchy feely kind of guy, I don't ever kiss a girl unless it's going somewhere, so someone using it as a sort of icebreaker would naturally seem 'off' to me personally. I don't know what kind of guy your target is, but if he's typically guyish in the samy way I am, it might freak him out.