Could I have done damage to my brain from all the drugs i've taken?

i've had a rough past, done many drugs, now i'm clean completely and i just can't find much happiness when im sober. in the past i've been addicted to benzos and opiates between the ages of 18 and 21.

i've done mdma over 10 times
xanax over 100 times
oxycodone over 100 times
heroin over 100 times

yes, lots of drugs. is it possible that throughout all of this i've done real damage to my brain that actually doesn't let me feel happiness like everyone else?
Could I have done damage to my brain from all the drugs i've taken?
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