If thick genes run in my family will I have a hard time loosing weight and keeping it off even if I do all the right things like eating healthy etc?

In my family most of the women are thick and short, Not FAT but overweight. I'm 5'1 and I weigh 150 my mom is about 5'3 and she's thick too I don't know her exact weight but it's more then me for sure. It's crazy because we don't look fat or obese we just mainly have stomach and thick thighs. Also most of my female cousins are short too and thick like that. My mother said my great grandma was like that too. If this is genetic am I out of luck with acheiveing a nice fit body?
If thick genes run in my family will I have a hard time loosing weight and keeping it off even if I do all the right things like eating healthy etc?
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