If you smile at a guy and he doesn't smile back would you think he's not interested?

Anonymous
I am really bad at smiling especially when it comes to smiling at girls. Lots of girls smile and make eye contact with me but I usually don't smile back even if I think they are really attractive. I think this gives off the wrong message to most girls though, am I right?
If you smile at a guy and he doesn't smile back would you think he's not interested?
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