How to manipulate someone to stop liking someone?

My best friend (boy) likes this girl that clearly rejected him many times, but he would just not give up. It’s not healthy for him, because he misses many other chances, I’ve tried to talk him out of trying to win her, but he just wouldn’t listen and keeps wasting his time on her. I’ve come to the conclusion that I should use some kind of psychological technique on him in order for him to move on, because he’s not doing well run. Can you guys help please Cus I’m worried he’s gonna get his heart very very broken at the end
How to manipulate someone to stop liking someone?
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