Most efficient way to deal with a toxic person?

Toxic person: someone who creates drama and arguments frequently and for no reason, treats others poorly, uses others for their own gain, is manipulative, is conceited, and justifes their bad behavior whenever confronted. In your opinion, what is the most effective and mature way to deal with such people and their negative impacts on your own life?
Put up with them quietly
Confront them again and again, even though the outcome is always the same
Try to help them by being kind
Cut them out of your life
Select gender and age to cast your vote:
Most efficient way to deal with a toxic person?
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