My brother's wife doesn't seem to like me.

Well, my brother and his wife are both 24, they've been married for 2 years and they have a baby girl. His wife is a nice enough lady but I'm certain she doesn't like me or she has something against me. My brother has said that she often talks negatively about me to him and of course this bothers him because we are very close. She even once called me a "f***ing whore" (um, which I'm not), in front of me at a family gathering. I know that this is creating a rift in their relationship and I feel terrible about it. Should I confront her directly about this issue to see what's really going on? My brother won't talk to her about it.
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LOL, just realized I put this in the wrong category - was supposed to be in Relationships. Anyways, thanks for your answers.
My brother's wife doesn't seem to like me.
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