Why do girls tend to automatically assume I'm romantically or sexually interested in them when I try to have a conversation with them?

Physics-Man
I've always had few female friends because of this. It doesn't matter what topic it is; they always take it the same way, and become defensive and closed!
This is why it's so much easier for me to make male friends than female ones; guys don't think you're doing it due to some romantic or sexual interest, but as a friendly reason. Is this strictly due to sex similarities or differences?
Why do girls tend to automatically assume I'm romantically or sexually interested in them when I try to have a conversation with them?
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