Is possible that one girl can ruin it for the rest for him?

I know a guy and he really one girl. They were seeing each other for a while but then she turned him down. He was really sad. He has more opportunities but he just doesn't care anymore. He could have many pretty girls but he is not interested. Always when someone brings up a girl in conversation for him or suggests him to approach some he just says what is the point and it will end up the same as last time. One girl broke his heart and he throws now all to the same bag.

Is possible that one girl can ruin it for the rest for him?
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