How long does it take a once-a-day medicine to leave your system?

Anonymous
I know this might seem like a silly question and the answer might be 24 hours. But say you miss your blood pressure medicine by like 8 hours and then take it (so you go 36 hours instead of 24)

Will the affect of the medicine be gone by then? Or is there some overlap?
How long does it take a once-a-day medicine to leave your system?
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